7 NYC startups to know
Life Sciences AI
Drug discovery, computational biology, lab automation, and AI-native biotech infrastructure built in New York.
Why this category matters
Life sciences AI fits the map where New York teams use models to reason over biology, design medicines, and build infrastructure for lab and biotech workflows.
Startups to know in Life Sciences AI
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Drug programs can be steered using continually updated evidence and probability-of-success estimates, helping identify patient subgroups and change course during trials
Pathos AI develops oncology drugs using Foundry, an agentic platform that continuously analyzes clinical evidence to select assets and guide development decisions.
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AI-led scientific workflows can connect patient evidence to testable hypotheses, with biomedical experts and wet labs validating promising results
Owkin develops K Pro, an autonomous AI scientist that combines multimodal patient data, specialized agents, and laboratory validation to investigate biomedical questions.
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The physical execution layer for autonomous science
Opentrons connects AI models to open laboratory robots, turning experiment design, execution, and structured results into a continuous learning loop for autonomous science.
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Drug development can advance faster when clinical assets, operational workflows, and accumulated evidence are coordinated through software rather than fragmented manual processes
Formation Bio acquires clinical-stage medicines and develops them using an AI-native platform, combining drug selection, trial operations, and reusable data infrastructure.
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Proxima Bio, formerly VantAI, is an AI-native platform for proximity-based drug discovery, mapping protein-protein interactions to design medicines that reshape protein networks rather than inhibit single targets
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Scientific AI can become more useful by learning the mechanisms behind complex systems and using those explanations to guide new investigations
Output Labs develops AI systems for mechanistic reasoning, aiming to model how complex systems work and apply those explanations to scientific problems.
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Find therapeutic targets hidden in RNA splicing
Envisagenics analyzes RNA splicing with AI to identify disease-specific drug targets, advancing therapeutic discovery for cancer and neurodegenerative conditions through its SpliceCore platform.
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